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All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner mitochondrial membranes in eukaryotes and in cytosol in prokaryotes. This enzyme is:

  1. A
    lactate dehydrogenase
  2. B
    isocitrate dehydrogenase
  3. C
    malate dehydrogenase
  4. D
    succinate dehydrogenase

Solution & Step-by-step Explanation

Succinate dehydrogenase is the only enzyme of the Krebs cycle that is membrane-bound. In eukaryotes, it is located in the inner mitochondrial membrane and also functions as Complex II in the Electron Transport Chain.

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All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner mitochondrial membranes in eukaryotes and in cytosol in prokaryotes. This enzyme is:
A
lactate dehydrogenase
B
isocitrate dehydrogenase
C
malate dehydrogenase
D
succinate dehydrogenase

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