Anaphase promoting complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur?
- AChromosomes will not condense
- BChromosomes will be fragmented
- CChromosomes will not segregate
- DRecombination of chromosome arms will occur
Solution & Step-by-step Explanation
The APC triggers the transition from metaphase to anaphase by marking specific proteins for degradation, which allows sister chromatids to separate. If APC is defective, the sister chromatids will stay attached, and chromosomes will fail to segregate.