It is possible to detect the mutated gene causing cancer by allowing radioactive probe to hybridise its complementary DNA in a clone of cells, followed by its detection using autoradiography because:
- Amutated gene does not appear on a Photographic film as the probe has no complementarity with it
- Bmutated gene does not appear on Photographic film as the probe has complementarity with it
- Cmutated gene partially appears on a photographic film
- Dmutated gene completely and clearly appears on a photographic film
Solution & Step-by-step Explanation
[Image showing the process of autoradiography for detecting mutated genes]A single-stranded DNA/RNA tagged with a radioactive molecule (probe) is allowed to hybridize to its complementary DNA in a clone of cells. The mutated gene will not appear on the photographic film because the probe was designed for the normal gene and will have no complementarity with the mutated sequence.