Pointing towards Aneesh, a woman said, "His mother is the only daughter of my mother." How is the woman related to Aneesh?

Let's analyze the description given by the woman:
1. "The only daughter of my mother" $⟹$ Since the speaker is a woman herself, her mother's only daughter must be the woman herself.
2. Substituting this back into the statement: "His (Aneesh's) mother is myself (the woman)."

Therefore, the woman is the Mother of Aneesh.