Prosthetic groups differ from co-enzymes in that:
- Athey require metal ions for their activity.
- Bthey are tightly bound to apoenzymes.
- Ctheir association with apoenzymes is transient.
- Dthey can serve as co-factors in many reactions.
Solution & Step-by-step Explanation
Both are organic co-factors. However, prosthetic groups are tightly bound to the apoenzyme (e.g., Haem in peroxidase), while co-enzymes have a transient (temporary) association usually during the course of catalysis.