Select the combination of letters that when sequentially placed in the blanks of the given series will complete the series.
_ NE CIN _ C _ M

Let's analyze the pattern by testing the options to complete the sequence of length 18.
If we use option D (IMCEANEMAME), the filled letters are:
1st blank = I
2nd blank = M
3rd blank = C
4th blank = E
5th blank = A
6th blank = N
7th blank = E
8th blank = M
9th blank = A
10th blank = M
11th blank = E

Substituting these into the given expression:
I M N E C E C I N A N E C M A M M E

Let's divide the letters into groups of 6 to check for a recurring keyword or pattern:

Group 1: I M N E C E

Group 2: C I N A N E

Group 3: C M A M M E

Let's check option B (CIMAEMAINEA):
Substituting option B:
C I N E M A C I N E M A C I N E M A

Let's split this full sequence of 18 letters into 3 groups of 6 letters each:

C I N E M A

C I N E M A

C I N E M A

The word CINEMA repeats exactly 3 times.
Therefore, the sequence of filled letters must be: C, I, M, A, E, M, A, I, N, E, A.
This corresponds exactly to Option B.