Select the correct combination of mathematical signs that can sequentially replace the $\ast$ signs to balance the given equation.
$$13\ast 7\ast 12\ast 4\ast 15\ast 65$$

1. A
   $-,+,÷,\times ,=$
2. B
   $+,\times ,÷,\times ,=$
3. C
   $+,÷,\times ,+,=$
4. D
   $+,+,÷,\times ,=$