Select the most appropriate option to fill in the blank.
Conditions such as stress, depression and anxiety can all affect mental health and _________ a person’s routine.

Let's consider the context of a person's routine being affected by psychological conditions:
Fragment: Break or cause to break into fragments or pieces.

Crush: Deform, pulverize, or smash by force.

Dishevel: Make (a person's hair or clothes) untidy.

Disrupt: Interrupt an event, activity, or process by causing a disturbance or problem.

A daily routine or schedule is disrupted by mental health conditions. Hence, option D fits best.