Select the option that is related to the fifth letter-cluster in the same way as the second letter-cluster is related to the first letter-cluster and the fourth letter-cluster is related to the third letter-cluster.
PURE : IDGT :: COOL : VJJM :: LIPS : ?

The logic applied here is: $\text{Opposite letter}-2$ for each character in the cluster.
1. **PURE $\to$ IDGT**:
* Opposite of P is K (11) $\stackrel{-2}{\to }$ I (9)
* Opposite of U is F (6) $\stackrel{-2}{\to }$ D (4)
* Opposite of R is I (9) $\stackrel{-2}{\to }$ G (7)
* Opposite of E is V (22) $\stackrel{-2}{\to }$ T (20)

2. **COOL $\to$ VJJM**:
* Opposite of C is X (24) $\stackrel{-2}{\to }$ V (22)
* Opposite of O is L (12) $\stackrel{-2}{\to }$ J (10)
* Opposite of O is L (12) $\stackrel{-2}{\to }$ J (10)
* Opposite of L is O (15) $\stackrel{-2}{\to }$ M (13)

Applying the same rule to LIPS:

* Opposite of L is O (15) $\stackrel{-2}{\to }$ M (13)
* Opposite of I is R (18) $\stackrel{-2}{\to }$ P (16)
* Opposite of P is K (11) $\stackrel{-2}{\to }$ I (9)
* Opposite of S is H (8) $\stackrel{-2}{\to }$ F (6)

The final letter-cluster is MPIF.