Select the option which means the same as the group of words given.
To have a strong feeling of sympathy with a desire to help.

Let's check the definitions of the options:
Compassion: Sympathetic pity and concern for the sufferings or misfortunes of others, accompanied by a strong desire to alleviate it.

Apathy: Lack of interest, enthusiasm, or concern.

Gratitude: The quality of being thankful.

Brutality: Savage physical violence or great cruelty.

Hence, 'Compassion' is the perfect one-word substitute.