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hardMCQNEET 20172026Biology
4 marks (−1)

Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement:

  1. A
    Both are due to a qualitative defect in globin chain synthesis
  2. B
    Both are due to a quantitative defect in globin chain synthesis
  3. C
    Thalassemia is due to less synthesis of globin molecules
  4. D
    Sickle cell anemia is due to a quantitative problem of globin molecules

Solution & Step-by-step Explanation

- Sickle cell anemia is a qualitative defect; an incorrect amino acid (valine instead of glutamic acid) causes the globin to function poorly.Thalassemia is a quantitative defect; there is a reduced rate of synthesis of one of the globin chains ( or ), leading to fewer total hemoglobin molecules.

Practice this question

Try it yourself before checking the explanation above.

Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement:
A
Both are due to a qualitative defect in globin chain synthesis
B
Both are due to a quantitative defect in globin chain synthesis
C
Thalassemia is due to less synthesis of globin molecules
D
Sickle cell anemia is due to a quantitative problem of globin molecules

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