Which drug is used as an Anti-Histamine?

Both Fexofenadine and Promethazine have anti-histaminic properties. However, Fexofenadine is a second-generation selective ${\text{H}}_1$ blocker widely classified primarily as a standard non-drowsy anti-histamine drug used to treat allergy symptoms. Promethazine is primarily used as an antiemetic/sedative alongside its antihistamine properties. Ranitidine is an ${\text{H}}_2$ blocker (antacid) and Ibuprofen is an NSAID (analgesic/anti-inflammatory). Fexofenadine is the most accurate classical answer.