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Which non-essential amino acid is synthesised by the hydroxylation of phenylalanine in a reaction catalysed by phenylalanine hydroxylase?

  1. A
    Glutamine
  2. B
    Tyrosine
  3. C
    Cysteine
  4. D
    Glycine

Solution & Step-by-step Explanation

Tyrosine is a non-essential amino acid synthesized directly inside the human body by adding a hydroxyl group to the aromatic ring of the essential amino acid phenylalanine. This metabolic reaction is catalyzed by the enzyme phenylalanine hydroxylase. A deficiency of this functional enzyme results in a metabolic condition known as Phenylketonuria (PKU).

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Which non-essential amino acid is synthesised by the hydroxylation of phenylalanine in a reaction catalysed by phenylalanine hydroxylase?
A
Glutamine
B
Tyrosine
C
Cysteine
D
Glycine

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