Which of the following factors is responsible for the formation of concentrated urine?
- ALow levels of antidiuretic hormone
- BMaintaining hyperosmolarity towards inner medullary interstitium in the kidneys.
- CSecretion of erythropoietin by Juxtaglomerular complex
- DHydrostatic pressure during glomerular filtration
Solution & Step-by-step Explanation
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The countercurrent mechanism (involving Henle's loop and vasa recta) works to maintain hyperosmolarity in the inner medullary interstitium (300 to 1200mOsmol/L). This concentration gradient allows water to be reabsorbed from the collecting duct, resulting in the formation of concentrated urine.
The countercurrent mechanism (involving Henle's loop and vasa recta) works to maintain hyperosmolarity in the inner medullary interstitium (300 to 1200mOsmol/L). This concentration gradient allows water to be reabsorbed from the collecting duct, resulting in the formation of concentrated urine.