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During transcription, RNA polymerase holoenzyme binds to a gene promoter and assumes a saddle-like structure. What is its DNA-binding sequence?

  1. A
    TIAA
  2. B
    AATI
  3. C
    CACC
  4. D
    TATA

Solution & Step-by-step Explanation

The TATA box is a highly conserved DNA sequence found in the promoter region of many eukaryotic and prokaryotic genes. It serves as the binding site for transcription factors and RNA polymerase, helping to initiate the transcription process.

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During transcription, RNA polymerase holoenzyme binds to a gene promoter and assumes a saddle-like structure. What is its DNA-binding sequence?
A
TIAA
B
AATI
C
CACC
D
TATA

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Molecular BiologyTranscriptionGenetics

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