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Molecular Biology Questions

Practice 60 Molecular Biology questions with detailed answers and explanations. Free MCQs, PYQs, and mock test questions for NEET, JEE, GATE, SSC and more.

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20
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38
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2
Hard
Practice by Exam:Biology(60)

About Molecular Biology — practice questions, PYQs & concepts

Molecular Biology is a frequently-tested topic on Biology. ExamTest.live currently lists 60 Molecular Biology questions spanning previous-year papers from 2026 to 2026, each with worked solutions and a step-by-step explanation. Use the filters on this page to focus on a specific exam, difficulty level or year — every answer key is free, no sign-up required.

Molecular Biology weight in competitive exams

Across our Molecular Biology question bank, the largest sources are Biology (60). Click any exam chip above to drill down to that exam-specific question set.

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All Molecular Biology Questions(1–60 of 60)

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Q1mediummcqBiologyNEET 20232026
Which one of the following is the sequence on corresponding coding strand, if the sequence on mRNA formed is: 5' -AUCGAUCGAUCGAUCGAUCG- 3’?
Q2mediummcqBiologyNEET (UG) 20182026
The correct order of steps in Polymerase Chain Reaction () is:
Q3easymcqBiologyNEET 20212026
Complete the flow chart on central dogma:
image
Q4mediummcqBiologyNEET 20212026
Identify the correct statement:
Q5easymcqBiologyNEET 20212026
What is the role of RNA polymerase III in the process of transcription in eukaryotes?
Q6easymcqBiologyNEET 20212026
Which of the following RNAs is not required for the synthesis of protein?
Q7mediummcqBiologyNEET 20212026
If Adenine makes 30% of the DNA molecule, what will be the percentage of Thymine, Guanine and Cytosine in it?
Q8easymcqBiologyNEET 20212026
Which is the "Only enzyme" that has "Capability" to catalyse Initiation, Elongation and Termination in the process of transcription in prokaryotes?
Q9easymcqBiologyNEET 20222026
The process of translation of mRNA to proteins begins as soon as:
Q10mediummcqBiologyNEET 20222026
Read the following statements and choose the set of correct statements:(a) Euchromatin is loosely packed chromatin(b) Heterochromatin is transcriptionally active(c) Histone octamer is wrapped by negatively charged DNA in nucleosome(d) Histones are rich in lysine and arginine.(e) A typical nucleosome contains bp of DNA helixChoose the correct answer from the options given below:
Q11hardmcqBiologyNEET 20222026
In an E. coli strain the i gene gets mutated and its product cannot bind the inducer molecule. If the growth medium is provided with lactose, what will be the outcome?
Q12mediummcqBiologyNEET 20222026
If the length of a DNA molecule is , what will be the approximate number of base pairs?
Q13easymcqBiologyNEET 20232026
Unequivocal proof that DNA is the genetic material was first proposed by:
Q14easymcqBiologyNEET 20232026
What is the role of RNA polymerase III in the process of transcription in Eukaryotes?
Q15easymcqBiologyNEET 20232026
Match List I with List II regarding the Lac Operon:| List I | List II || :--- | :--- || A. Gene 'a' | I. -galactosidase || B. Gene 'y' | II. Transacetylase || C. Gene 'i' | III. Permease || D. Gene 'z' | IV. Repressor protein |
Q16mediummcqBiologyNEET 20232026
Given below are two statements:Statement I: In prokaryotes, the positively charged DNA is held with some negatively charged proteins in a region called nucleoid.Statement II: In eukaryotes, the negatively charged DNA is wrapped around the positively charged histone octamer to form nucleosome.In the light of the above statements, choose the correct answer:
Q17hardmcqBiologyNEET 20222026
Ten E. coli cells with -dsDNA are incubated in a medium containing nucleotides. After minutes, how many E. coli cells will have DNA totally free from ?
Q18easymcqBiologyBiology
0% accuracy
Nucleotide are building blocks of nucleic acids, nucleotide is a composite molecule formed by:
Q19mediummcqBiologyBiology
0% accuracy
E. coli cells with a mutated Z gene of the lac operon cannot grow in medium containing only lactose as the source of energy because:
Q20mediummcqBiologyBiology
0% accuracy
Which one of the following hydrolyses internal phosphodiester bonds in a polynucleotide chain?
Q21mediummcqBiologyBiology
0% accuracy
During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle-like structure at that point. What is that sequence called?
Q22mediummcqBiologyBiology
0% accuracy
Telomerase is an enzyme which is a:
Q23mediummcqBiologyBiology
0% accuracy
What are those structures that appear as 'beads-on-string' in the chromosomes when viewed under electron microscope?
Q24mediummcqBiologyBiology
0% accuracy
Which one of the following also acts as a catalyst in a bacterial cell?
Q25mediummcqBiologyBiology
Select the correct option regarding the direction of RNA synthesis and the reading of the template DNA strand:
Q26mediummcqBiologyBiology
Which one of the following is wrongly matched?
Q27mediummcqBiologyBiology
Which enzyme/s will be produced in a cell in which there is a non-sense mutation in the lac Y gene?
Q28easymcqBiologyBiology
The central dogma of molecular biology, which describes the flow of genetic information, was proposed by:
Q29mediummcqBiologyBiology
Removal of RNA polymerase III from nucleoplasm will affect the synthesis of:
Q30mediummcqBiologyBiology
If one strand of DNA has the nitrogenous base sequence as ATCTC, what would be the complementary RNA strand sequence?
Q31easymcqBiologyBiology
Which one of the following is NOT a part of a transcription unit in DNA?
Q32mediummcqBiologyBiology
Removal of introns and joining of exons in a defined order during transcription is called:
Q33easymcqBiologyBiology
The central dogma of molecular genetics states that the genetic information flows from:
Q34easymcqBiologyBiology
Which one of the following does NOT follow the central dogma of molecular biology?
Q35mediummcqBiologyBiology
A sequential expression of a set of human genes occurs when a steroid molecule binds to the:
Q36mediummcqBiologyBiology
During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point. What is that sequence called ?
Q37mediummcqBiologyBiology
Which one of the following hydrolyses internal phosphodiester bonds in a polynucleotide chain ?
Q38mediummcqBiologyBiology
Which one of the following statements is true for protein synthesis (translation)?
Q39mediummcqBiologyBiology
cDNA probes are copied from the messenger RNA molecules with the help of:
Q40mediummcqBiologyBiology
Assertion : Replication and transcription occur in the nucleus but translation occurs in the cytoplasm.Reason : mRNA is transferred from the nucleus into the cytoplasm where ribosomes and amino acids are available for protein synthesis.
Q41mediummcqBiologyBiology
Molecular basis of organ differentiation depends on the modulation in transcription by:
Q42mediummcqBiologyBiology
The length of DNA molecule greatly exceeds the dimensions of the nucleus in eukaryotic cells. How is this DNA accommodated?
Q43mediummcqBiologyBiology
During transcription, RNA polymerase holoenzyme binds to a gene promoter and assumes a saddle-like structure. What is its DNA-binding sequence?
Q44mediummcqBiologyBiology
Differentiation of organs and tissues in a developing organism is associated with:
Q45mediummcqBiologyBiology
The Okazaki fragments in DNA chain growth:
Q46mediummcqBiologyBiology
The two polynucleotide chains in DNA are:
Q47mediummcqBiologyBiology
One gene-one enzyme relationship was established for the first time in:
Q48mediummcqBiologyBiology
Select the two correct statements about the lac operon:(a) Glucose or galactose may bind with the repressor and inactivate it.(b) In the absence of lactose the repressor binds with the operator region.(c) The -gene codes for permease.(d) This was elucidated by Francois Jacob and Jacques Monod.
Q49easymcqBiologyBiology
Which pair of nitrogenous bases is wrongly matched with its category?
Q50easymcqBiologyBiology
In the DNA molecule:
Q51easymcqBiologyBiology
Which one of the following pairs of codons is correctly matched with its function?
Q52mediummcqBiologyBiology
Polyethylene glycol () method is used for:
Q53mediummcqBiologyBiology
What is NOT true for the genetic code?
Q54easymcqBiologyBiology
Removal of introns and joining the exons in a defined order in a transcription unit is called:
Q55easymcqBiologyBiology
Semiconservative replication of was first demonstrated in:
Q56mediummcqBiologyBiology
Whose experiments cracked the DNA and discovered unequivocally that a genetic code is a "triplet"?
Q57easymcqBiologyBiology
Point mutation involves:
Q58easymcqBiologyBiology
The one aspect which is NOT a salient feature of the genetic code is its being:
Q59mediummcqBiologyBiology
Satellite is a useful tool in:
Q60mediummcqBiologyBiology
Telomerase is an enzyme which is a :

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