Molecular Biology Questions

Telomerase is an enzyme which is a:

During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle-like structure at that point. What is that sequence called?

Which one of the following hydrolyses internal phosphodiester bonds in a polynucleotide chain?

E. coli cells with a mutated Z gene of the lac operon cannot grow in medium containing only lactose as the source of energy because:

Nucleotide are building blocks of nucleic acids, nucleotide is a composite molecule formed by:

Which one of the following also acts as a catalyst in a bacterial cell?

What are those structures that appear as 'beads-on-string' in the chromosomes when viewed under electron microscope?

If one strand of DNA has the nitrogenous base sequence as ATCTC, what would be the complementary RNA strand sequence?

Semiconservative replication of $\text{DNA}$ was first demonstrated in:

Whose experiments cracked the DNA and discovered unequivocally that a genetic code is a "triplet"?

Point mutation involves:

The one aspect which is NOT a salient feature of the genetic code is its being:

Satellite $\text{DNA}$ is a useful tool in:

Which one of the following does NOT follow the central dogma of molecular biology?

Select the two correct statements about the lac operon:(a) Glucose or galactose may bind with the repressor and inactivate it.(b) In the absence of lactose the repressor binds with the operator region.(c) The $z$ -gene codes for permease.(d) This was elucidated by Francois Jacob and Jacques Monod.

Removal of introns and joining of exons in a defined order during transcription is called:

Which one of the following is NOT a part of a transcription unit in DNA?

Which one of the following pairs of codons is correctly matched with its function?

Removal of RNA polymerase III from nucleoplasm will affect the synthesis of:

The central dogma of molecular biology, which describes the flow of genetic information, was proposed by:

Which enzyme/s will be produced in a cell in which there is a non-sense mutation in the lac Y gene?

Which one of the following is wrongly matched?

Select the correct option regarding the direction of RNA synthesis and the reading of the template DNA strand:

The central dogma of molecular genetics states that the genetic information flows from:

The Okazaki fragments in DNA chain growth:

During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point. What is that sequence called ?

Which one of the following hydrolyses internal phosphodiester bonds in a polynucleotide chain ?

Which one of the following statements is true for protein synthesis (translation)?

cDNA probes are copied from the messenger RNA molecules with the help of:

Assertion : Replication and transcription occur in the nucleus but translation occurs in the cytoplasm.Reason : mRNA is transferred from the nucleus into the cytoplasm where ribosomes and amino acids are available for protein synthesis.

Molecular basis of organ differentiation depends on the modulation in transcription by:

The length of DNA molecule greatly exceeds the dimensions of the nucleus in eukaryotic cells. How is this DNA accommodated?

During transcription, RNA polymerase holoenzyme binds to a gene promoter and assumes a saddle-like structure. What is its DNA-binding sequence?

Differentiation of organs and tissues in a developing organism is associated with:

Removal of introns and joining the exons in a defined order in a transcription unit is called:

The two polynucleotide chains in DNA are:

One gene-one enzyme relationship was established for the first time in:

A sequential expression of a set of human genes occurs when a steroid molecule binds to the:

Which pair of nitrogenous bases is wrongly matched with its category?

In the DNA molecule:

Telomerase is an enzyme which is a :

Polyethylene glycol ($\text{PEG}$) method is used for:

What is NOT true for the genetic code?